Visual Abstract

Scientific Diagrams & Illustrations

ADC Structure

1. ADC Molecular Structure

Complete Antibody-Drug Conjugate architecture showing the antibody, linker, and cytotoxic payload components

Th17 & RORγt

2. Th17 Cell & RORγt Receptor

Target receptor on disease-causing Th17 cells, showing nuclear localization of the RORγt transcription factor

Mechanism

3. Mechanism of Action

Four-step ADC mechanism: cell targeting → receptor binding → internalization → payload release

Comparison

4. ADC vs. Traditional Therapy

Comparative analysis demonstrating precision targeting advantages over broad systemic exposure

Docking

5. Molecular Docking Results

Computational docking visualization showing key molecular interactions and binding mechanisms

Pathway

6. Disease Pathway & Intervention

Illustration of how ADC technology blocks the autoimmune inflammatory cascade at the cellular level